RESULTS OF CYTOLOGICAL SCREENING IN WOMEN OF DIFFERENT AGE GROUPS AS PART OF COMPREHENSIVE MEDICAL EXAMINATIONS
DOI:
https://doi.org/10.32782/2786-7684/2025-4-16Keywords:
cytological screening, medical examinations, PAP testAbstract
Introduction. Cervical cytological screening is a preventive examination method designed to detect pathological changes at an early stage. This examination makes it possible to detect gynecological pathologies (in particular, cervical cancer) at an early stage, when symptoms are not yet present. Objective. To analyze the results of cytological screening among women of different age groups who underwent a comprehensive medical examination. Materials and methods. Cytological screening was performed using the classic PAP test. The type of smear was determined based on the description of the smears. A clinical and statistical analysis of the results of cytological screening of women of different age groups (18–29 years, 30–39 years, 40–49 years, 50 years and older) who underwent a comprehensive medical examination was performed. Results. It was found that atypical changes (mild dysplasia, 1.3% of all cases) were recorded exclusively in women over 50 years of age. The frequency of inflammatory smears depended on age: in women of reproductive age, it was up to 41.4%, while in postmenopausal women, this figure was almost three times lower (15.2%). These differences are probably related to hormonal status and sexual activity. Conclusions. The data obtained indicate the need for periodic comprehensive medical examinations, including visits to a gynecologist and cancer screening.
References
Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. Lancet. 2019;393(10167):169–82. DOI: 10.1016/S0140-6736(18)32470-X.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6). DOI: 10.3322/caac.21492.
Standart med dopomohy «Skryning raku shyyky matky. Vedennia patsiientok z anomalnymy rezultatamy skryninhu ta peredrakovymy stanami shyyky matky. 2024. 11 s. Available from: https://moz.gov.ua/storage/uploads/3b9b0fce-86b2-409c-979a-969e67b76929/dn_1057_18062024_dod.pdf.
Nastanova 00533. Pap-test (shyyky matky) ta biopsiia endometriiu. 2017-08-09. 9 s. Available from: https://guidelines.moz.gov.ua/documents/3365.
Biuleten natsionalnoho kantser-reiestru Ukrainy, № 25. Kyiv; 2024. Available from: http://www.ncru.inf.ua/publications/BULL_25/index.htm#zmist.
Kyrgiou M, Athanasiou A, Paraskevaidi M, Paraskevaidis E, Nieminen P, Kalliala I, та ін. Cervical screening: ESGO- EFC position paper of the European Society of Gynaecologic Oncology (ESGO) and the European Federation of Colposcopy (EFC). Br J Cancer. 2020;123(4):510–7. DOI: 10.1038/s41416-020-0920-9.
Todoryko VP, Tsysar YuV. Suchasnyi pohliad na diahnostyku ta skrynhinh raku shyiky matky (ohliad literatury). The 2nd International scientific and practical conference “Global science: prospects and innovations” (October 5–7, 2023). 2023. s. 194–9.
Kravchenko OV, Yasnikovska SM, Pecheriaha SV. Suchasni laboratorni ta instrumentalni metody doslidzhennia osnovnoi hinekolohichnoi patolohii. Chernivtsi: BDMU; 2025. 120 s.
Nayar R, Wilbur DC. The bethesda system for reporting cervical cytology: Definitions, criteria, and explanatory notes. Springer International Publishing; 2015. DOI: 10.1159/000477556.
Riley L. Monitoring cervical cancer: screening and treatment coverage. Presentation using the WHO Steps Survey (cervical cancer screening) [Internet]. 2019. Available from: https://apps.who.int/iris/handle/10665/275391.
Burka IA. Skryning raku shyyky matky: PAP-test, tsytolohiia, VPL-test? Zdorov’ia Ukrainy. 2021;(4):29–30. Available from: https://health-ua.com/multimedia/userfiles/files/2021/Akush_4_2021/Akush_4_2021_st_29_30.pdf.
Eliminating cervical cancer [Editorial]. Lancet. 2020 Feb 1;395(10221):312. DOI: 10.1016/S0140-6736(20)30247-6.
Kenidra AYu, Feisa SV. Tsytolohichnyi skryning raku shyyky matky v Zakarpatskii oblasti. Wiad Lek. 2014;LXVII(2. cz. II):192–5. Available from: https://dspace.uzhnu.edu.ua/server/api/core/bitstreams/40a58338-d077-4631-a9f1-b4f1f687503c/content.
Prokopchuk TO, Poruchynska TF. Laboratorna diahnostyka slyzovykh obolonok shyyky matky zhinok v postmenopauzi. U: Patriak O, ta in., redaktory. Materialy Mizhnarodnoi multidystsyplinarnoi naukovoi internet-konferentsii (m. Ternopil, Ukraina, m. Opole, Polshcha, 19–20 veresnia 2024 r.). Ternopil: FO-P Shpak VB; 2024. s. 162–4.
Kozyratska LM, Lahovska HI, Kovalchuk TYu. Tsytolohichnyi skrynin-efektyvnyi metod profilaktyky raku shyyky matky. Mahistr medsesternystva. 2022;1(27):86–91. Available from: https://www.zhim.org.ua/magazine/visnyk_mag_med_2021_1.pdf







